Bronchogen
Also called ADEL; Ala-Asp-Glu-Leu
A four-amino-acid research peptide studied in airway cells and experimental lung-injury models. It has not been shown to improve breathing or treat COPD in people.
Overview
What it is
A tetrapeptide from the Khavinson bioregulator literature. Sources list its sequence differently (Ala-Asp-Glu-Leu vs Ala-Glu-Asp-Leu), so the exact identity should be confirmed against the batch documentation.
How it works
In cultured human airway-lining cells, it changed proteins tied to cell growth and survival and genes tied to airway-cell maturation, and it interacted with DNA in a lab system. Gene-expression changes do not show that someone breathes more easily.
What the research shows
In a 2015 rat model of lung damage from nitrogen dioxide, Bronchogen improved several tissue and inflammation measures. An earlier tissue-culture study reported growth responses in rat lung samples. No controlled human trial showing better lung function or fewer hospital visits was identified.
Studied for
- Airway cell gene expressionlab
- Obstructive lung damagerats
Safety and regulatory status
Safety and side effects
No dependable human side-effect profile, safe repeated-use schedule or interaction data with respiratory medications exists. Never substitute a research peptide for prescribed inhalers or oxygen.
Regulatory status
Not approved by the FDA for any use.
Mixing and dosing reference
Reference information only. Read before using this section.
Bronchogen (20 mg Vial) Dosage Protocol
- Vial
- 20 mg Bronchogen
- Add diluent
- 3 mL
- Concentration
- 6.67 mg/mL
- 1 unit (U-100)
- 66.67 mcg in 0.01 mL
- Route
- Subcutaneous
Community-Reported Use Calculations
| Research Period | Amount per Administration | U-100 Units (mL) |
|---|---|---|
| 10 days | 1 mg | 15 units (0.15 mL) |
| 20 days | 1 mg | 15 units (0.15 mL) |
| 10 days | 2 mg | 30 units (0.30 mL) |
| 20 days | 2 mg | 30 units (0.30 mL) |
How to mix
- Clean the vial stopper and diluent stopper with alcohol; allow both to dry.
- Draw exactly 3.0 mL of bacteriostatic water with a new sterile syringe, then inject it slowly down the inside wall of the vial.
- Gently swirl or roll until dissolved. Do not shake.
- Label the vial with compound, concentration, and preparation date. Store it according to verified product-specific instructions.
Protocol source: PeptideDosages.com
Common questions
Is Bronchogen the same as Chonluten?
No. They are different peptides with separate research.
Why do some studies mention human cells?
Human cells grown in a lab are useful for research but are not a human treatment trial.
What would make the evidence stronger?
Confirmed identity, independent replication and controlled human studies measuring breathing outcomes.
Related in Healthy Aging
Sources and further reading (5)
- Khavinson VKh, et al. ADEL gene expression in bronchial epithelium. Lung, 2014.
- Short peptides and differentiation in aging tissue cultures, 2012.
- Bronchogen in a rat model of obstructive lung pathology, 2015.
- Synthetic bioregulatory peptides in young and old rat tissue cultures. Advances in Gerontology, 2006.
- Source summary: PeptideDosages.com research overview (rewritten for NVO).