CJC-1295 + GHRP-2 blend
Also called CJC/GHRP-2
A research blend pairing a GHRH analogue with a ghrelin-receptor secretagogue. The pathway rationale is real, but the blend itself has not been tested in people.
Overview
What it is
CJC-1295 (a GHRH analogue) plus GHRP-2 (pralmorelin). See each ingredient's entry.
How it works
GHRH and ghrelin-receptor pathways can boost growth hormone release together in human research, though the studied compounds and routes differ from this blend.
What the research shows
CJC-1295 with DAC raised growth hormone and IGF-1 for days in healthy adults. GHRP-2 raises growth hormone and appetite acutely. No trial of the blend was identified.
Studied for
- Growth hormone releaseingredients separately
Safety and regulatory status
Safety and side effects
GHRP-2 can increase appetite and briefly raise ACTH, cortisol and prolactin; CJC-1295 can cause flushing and lightheadedness. FDA lists both on its compounding safety-risk list.
Regulatory status
Not FDA approved. Both ingredients are prohibited in sport.
Mixing and dosing reference
Reference information only. Read before using this section.
CJC-1295 + GHRP-2 (10 mg Blend) Dosage Protocol
- Vial
- 10 mg total blend
- Add diluent
- 3 mL
- Concentration
- 3.33 mg/mL
- 1 unit (U-100)
- 33.33 mcg total in 0.01 mL
- Route
- Subcutaneous
- How often
- Once per day (subcutaneous), preferably evening/bedtime.
- Typical range
- 100–300 mcg once daily (gradual titration).
- Cycle length
- 8–12 weeks; optional extension to 16 weeks.
Standard / Gradual Approach
| Week | Daily Dose (mcg) | Units (per injection) (mL) |
|---|---|---|
| Weeks 1–2 | 150 mcg (0.15 mg) | 4.5 units (0.045 mL) |
| Weeks 3–12 | 300 mcg (0.30 mg) | 9 units (0.09 mL) |
Advanced / Twice-Daily Approach
| Week | Dose per Injection (mcg) | Units (per injection) (mL) | Total Daily (mcg) |
|---|---|---|---|
| Weeks 1–2 | 100 mcg (0.10 mg) | 3 units (0.03 mL) | 200 mcg |
| Weeks 3–12 | 150 mcg (0.15 mg) | 4.5 units (0.045 mL) | 300 mcg |
How to mix
- Draw 3.0 mL bacteriostatic water with a sterile syringe.
- Inject slowly down the vial wall; avoid foaming.
- Gently swirl/roll until dissolved (do not shake).
- Label and refrigerate at 2–8 °C (35.6–46.4 °F), protected from light.
Dosing details
- Start: 100–150 mcg daily for Weeks 1–2 to allow acclimatization.
- Target: 250–300 mcg daily by Weeks 3–12.
- Frequency: Once per day (subcutaneous), preferably evening/bedtime.
- Cycle Length: 8–12 weeks; optional extension to 16 weeks.
- Timing: Inject on an empty stomach; rotate injection sites.
Storage
- Lyophilized: Follow each component vial’s labeled storage temperature and expiration instructions.
- Reconstituted: Refrigerate at 2–8 °C (35.6–46.4 °F); follow formulation-specific use-by and sterile-handling instructions.
- Allow vials to reach room temperature before opening to reduce condensation uptake.
- Do not assume aliquoting or freezing a reconstituted blend extends stability or sterility; avoid repeated freeze–thaw.
Administration technique
- Clean the vial stopper and skin with alcohol; allow to dry.
- Pinch a skinfold; insert the needle at 45–90° into subcutaneous tissue.
- Do not aspirate for subcutaneous injections; inject slowly and steadily.
- Rotate sites systematically (abdomen, thighs, upper arms) to avoid local tissue changes.
- Withdraw the needle at the same angle; dispose immediately in a sharps container.
Important notes
- Use new sterile insulin syringes for each injection; dispose in a sharps container.
- Rotate injection sites (abdomen, thighs, upper arms) to reduce local irritation.
- Inject slowly on an empty stomach; GHRP-2’s GH response may be blunted by elevated blood glucose.
- Document daily dose and site rotation to maintain consistency.
- No post-cycle therapy is required; GH and IGF-1 levels return to baseline after cessation.
Protocol source: PeptideDosages.com
Common questions
Does combining them work better?
Pathway research suggests a larger GH response, but no trial shows better health outcomes.
Related in Performance and Recovery
Sources and further reading (3)
- Teichman SL, et al. CJC-1295 in healthy adults. JCEM, 2006.
- Laferrère B, et al. GHRP-2 increases food intake, 2005.
- Source summary: PeptideDosages.com research overview (rewritten for NVO).